Advanced Physiology and Pathophysiology
Essentials for Clinical Practice
Linda Herrmann, PhD, RN, ACHPN, AGACNP-BC, GNP-BC, FAANP
Nancy C. Tkacs, PhD, RN
Understand Disease Mechanisms, Apply Knowledge, and Think Like a Clinician.
About This Text
This concise, well-organized text links normal physiology to the pathophysiology of common disorders and shows how mechanisms guide diagnostics and management. Learn why patients present with specific symptoms, how to interpret results, and how to translate science into clinical decisions. Includes case studies, more than 500 images, and end-of-chapter key points.
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What’s New in the Second Edition
- Physiology of pregnancy, labor, and delivery
- Expanded neonatal and pediatric development section
- Cell-free DNA methylation (epigenetics) patterns in oncology
- Expanded fluid and electrolyte balance section
- Enhanced section on the social determinants of health
- Introduction of the exposome concept in human disease
- Updates on biological and psychosocial aspects of sexual development, including LGBTQ+-centered care
Why Students Love This Text
- Clear, concise content connects physiology to pathophysiology and real-life care
- Bridge to Clinical Practice sections help translate concepts to practical patient care.
- Over 500 full-color images illustrate and simplify complex ideas
- Case studies and critical-thinking questions build clinical decision-making skills
- Chapter summaries and key points reinforce learning
- Comprehensive lifespan coverage from pediatric to geriatric care
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Case Studies
Foreword by Joshua E. Faucett, DNP, MBA, FNP-BC, CNE
Acknowledgements
Contributors
Case Study Contributors
How to Use This Book
Instructor Resources
Chapter 1 The Foundational Concepts of Clinical Practice
Chapter 2 Chemical and Biochemical Foundations
Chapter 3 Molecular Biology, Genetics, and Genetic Diseases
Chapter 4 Cell Physiology and Pathophysiology
Chapter 5 Infectious Disease
Chapter 6 The Immune System and Leukocyte Function
Chapter 7 Neoplasia
Chapter 8 Blood and Clotting
Chapter 9 Circulation
Chapter 10 Heart
Chapter 11 Lungs
Chapter 12 Kidneys
Chapter 13 Gastrointestinal Tract
Chapter 14 Liver
Chapter 15 Nervous System
Chapter 16 Musculoskeletal System
Chapter 17 Endocrine System
List of Abbreviations
Index
List of Disorders
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- Release Date: March 27, 2024
- Paperback / softback
- 888 Pages
- Trim Size: 8.5in x 11in
- Number of Illustrations: 500
- ISBN: 9780826167552
- eBook ISBN: 9780826167545



















