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Head and Neck Cancers

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Head and Neck Cancers

SKU# 9780826137777

Evidence-Based Treatment


  • Athanassios Argiris MD, FACP
  • Robert L. Ferris MD, PhD, FACS
  • David I. Rosenthal MD, FACR, FASTRO
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Head and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy.

Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes.

Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies.

Key Features:

  • Includes didactic clinical cases for each type of head and neck cancer
  • Numerous tables highlight FDA approved therapies and ongoing clinical trials
  • Provides evidence-based recommendations for treating head and neck cancers at each stage of the disease with conventional and novel treatment strategies
  • Covers strategies for managing acute and late complications to treatment
  • Includes access to the fully-searchable downloadable e-book

Product Details 

  • Publication Date July 09, 2018
  • Page Count 550
  • Product Form Hardback
  • ISBN 13 9780826137777
  • EISBN 9780826137784

Table of Contents 





Epidemiology, Biology, Diagnosis, and Staging

1. Head and Neck Cancer Epidemiology

Angela L. Mazul, Erich M. Sturgis, Andrew F. Olshan, and Jose P. Zevallos

2. Pathology of HNSCC

Michelle D. Williams and Adel K. El-Naggar

3. The Genomic Landscape of HNSCC

Steffen Wagner, Jens P. Klussmann, and Ruud H. Brakenhoff

4. HPV-Related Head and Neck Cancer Biology

Farhoud Faraji and Carole Fakhry

5. Imaging of Head and Neck Cancers

Rathan M. Subramaniam


Established and Emerging Treatment Modalities

6. Advances in Radiation Therapy Techniques for HNSCC: Image-Guided RT Stereotactic, IMRT-VMAT, MRI-Linac and Simulation

Jussi Sillanpaa, C. Jillian Tsai, and Nancy Y. Lee

7. Proton Therapy

Pierre Blanchard, G. Brandon Gunn, and Steven J. Frank

8. Transoral Robotic Surgery: Advances and Applications

Meghan T. Turner, F. Christopher Holsinger, and Robert L. Ferris

9. Induction Chemotherapy: Current and Emerging Role in HNSCC

Glenn J. Hanna and Robert I. Haddad

10. Immunotherapy for HNSCC: Rationale and Clinical Applications

Jennifer Moy, Jennifer M. Johnson, Jessica Moskovitz, Robert L. Ferris, and Athanassios Argiris

11. Targeting the Human Epidermal Receptor Family in HNSCC

Emmanuel Seront, Sandra Schmitz, and Jean-Pascal Machiels

12. Therapies Targeting VEGF/Angiogenesis and Other Novel Targets and Therapies in HNSCC

Sophie Stock-Martineau, Yanqun Dong, Denis Soulières, and Thomas J. Galloway


Site-Specific Management

13. Oropharyngeal Cancer: HPV-Positive Disease

Christien A. Kluwe, Anthony J. Cmelak, and Barbara A. Burtness

14. Non–HPV-Associated Oropharyngeal Cancer

Meghan T. Turner, Anirudh Saraswathula, and F. Christopher Holsinger

15. Oral Cavity Cancer: Surgical Approaches and Postoperative Treatment

Antoine Eskander, Jacques Bernier, Lisa Licitra, Paolo Bossi, and Theodoros N. Teknos

16. Nasopharyngeal Cancer

Wai Tong Ng, Oscar S. H. Chan, Henry C. K. Sze, Ka On Lam, and Anne W. M. Lee

17. Hypopharyngeal Cancer: A Multidisciplinary Approach

Moran Amit, Loren K. Mell, Cristina P. Rodriguez, and Neil D. Gross

18. Laryngeal Cancer: Organ Preservation Strategies

Arlene A. Forastiere, Jae Lee, Steven B. Chinn, Karim Boudadi, Avraham Eisbruch, Randal S. Weber

19. Malignancies of the Paranasal Sinuses and Skull Base

Heather A. Osborn, Jong Chul Park, Nabil F. Saba, Pierre Blanchard, and Derrick T. Lin

20. Evaluation and Treatment of Metastatic Lymphadenopathy From an Unknown Primary

Shirin Attarian, Richard Blake Ross, Shlomo A. Koyfman, and Missak Haigentz, Jr.

21. Salivary Gland Malignancies

Cristina P. Rodriguez, Jessica L. Geiger, Jon Mallen-St. Clair, Patrick K. Ha, Sue S. Yom, Adam S. Garden, and David J. Adelstein


Recurrent or Metastatic Disease

22. Locally Recurrent HNSCC: Salvage Surgery, Reirradiation

Antoine Eskander, Sharon A. Spencer, Corey J. Langer, Takashi Maruo, Ryuichi Hayashi, Sadamoto Zenda, and James W. Rocco

23. Recurrent or Metastatic HNSCC: Systemic Therapy

Tomohiro Enokida, Susumu Okano, and Makoto Tahara


Supportive Care and Special Patient Groups

24. Oral Complications

Rajesh V. Lalla and Douglas E. Peterson

25. Dysphagia in Patients With Head and Neck Cancer

Katherine A. Hutcheson and Jan S. Lewin

26. Quality of Life Assessment and Patient-Reported Outcomes in Head and Neck Cancer

Minh Tam Truong and Lisa Ann Kachnic

27. Management of Head and Neck Cancers in the Elderly

Jessica L. Geiger and Julie E. Bauman