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Fatigue in Multiple Sclerosis

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Fatigue in Multiple Sclerosis

SKU# 9781888799811

A Guide to Diagnosis and Management

Author: Lauren B. Krupp MD


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"This practical guide for physicians and other health care professionals discusses the impact of fatigue on the individual with MS, the potential etiologies underlying MS-related fatigue, its work up and diagnosis, and pharmacologic and nonpharmacologic management strategies.

Fatigue is perhaps the single most prevalent and disabling symptom of the multiple sclerosis, and limits patients' activity more than any other MS symptom. The identification of fatigue as a distinct clinical entity requires both art and science, and most of all, a willingness and ability to listen carefully to patients and their families. The physician's ability to obtain a comprehensive history requires a full understanding of the circumstances in which fatigue occurs (physical, cognitive, and psychosocial) and demands consideration of a large number of disorders, including anxiety, depression, excessive daytime sleepiness, pain, and spasticity, all of which may mimic or contribute to fatigue.

While fatigue is almost exclusively a subjective experience, depending on the patient's ability to understand and report this symptom, there are effective methods for identifying the existence of fatigue, determining its severity, and distinguishing it from related or contributing disorders such as depression, pain, and sleep disorders.

Readers will learn that fatigue need not be tolerated by the MS patient. Various therapies, support systems, and treatment of underlying affective disorders can all alleviate fatigue or reduce its impact, restoring the patient's energy levels and ability to participate in life. Virtually every MS patient with fatigue can benefit from intervention, and failing to treat the symptom of fatigue with the respect that it deserves is a serious detriment to patient care."

Product Details 

  • Publication Date March 01, 2004
  • Page Count 112
  • Product Form Paperback / softback
  • ISBN 13 9781888799811
  • EISBN 9781934559482

Table of Contents 

Introduction; What is Multiple Sclerosis-related fatigue?; The Measurement of Fatigue; The Pathophysiology of Multiple Sclerosis-Related Fatigue; Depression and Fatigue; The Examination and Diagnosis of Fatigue; Nonpharmacologic Approaches to Fatigue Management; The Pharmacologic Management of Fatigue; Appendix. Ensuring Patient Adherence to an Exercise Program.

Editorial Review(s) 

"Readable and informative... [It] logically explores the topic in a series of concise well-referenced chapters... Of use to neurologists, other physicians, and paramedical personnel who care for patients with MS [as well as] patients and their relatives looking for scientific information on fatigue in MS." -- The Lancet

"This is a delightful primer on an often very enigmatic subject. Lauren Krupp has succeeded in writing an invaluable resource on fatigue in MS... While there have been other publishing products on the subject, this small book will eclipse the others by virtue of its economy of style, focused approach, and user-friendly structure. 4 Stars!" -- Doody's Reviews