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Multiple Sclerosis and Related Disorders

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Multiple Sclerosis and Related Disorders

SKU# 9781936287758

Diagnosis, Medical Management, and Rehabilitation


  • Alexander Rae-Grant MD
  • Robert Fox MD
  • Francois Bethoux MD

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Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the Ïface of the diseaseÓ for patients, and present their own set of challenges for practitioners.

The book proceeds through diagnosis (initial symptoms, criteria and classification, imaging, lab tests, and differential diagnosis), approved treatments for the various MS types including emerging therapies where appropriate, symptom management, rehabilitative issues, general health and wellness, and an overview of MS clinical trials. Special populations, societal and family issues, and related disorders that are often mistaken for MS are also covered. Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporate newer diagnostic criteria. Because comorbidities often make the management of MS-related disability more complex, the book addresses these comorbidities as part of a comprehensive management plan.

To enhance the clinical utility, critical-to-know information and management pearls are boxed for quick reference and most chapters include lists of ÏKey PointsÓ for clinicians, and for patients and families. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout. The treatment chapters include specific recommendations where available and highlight areas of controversy. Illustrative cases go beyond the literature to amplify clinical recommendations and provide real-world guidance for practitioners. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout.

Multiple Sclerosis and Related Disorders features:

  • Comprehensive clinical reference for all members of the MS care team
  • Focus on practical approaches to diagnosis, treatment, counseling, and rehabilitative strategies
  • Reviews the latest disease modifying therapies
  • Extensive chapters on symptom management and women√ås issues in MS
  • Edited and written primarily by expert clinicians at Cleveland Clinic/Mellen Center
  • Evidence- and experience-based guidance
  • Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporating newer diagnostic criteria
  • Includes treatment guidelines and numerous illustrations, tables, scales key information is highlighted for quick reference

Product Details 

  • Publication Date June 18, 2013
  • Page Count 344
  • Product Form Hardback
  • ISBN 13 9781936287758
  • EISBN 9781617051272

Table of Contents 

"1. The History of Multiple Sclerosis; T. Jock Murray; 2. Overview of Multiple Sclerosis; Alexander Rae-Grant and Robert J. Fox; 3. Pathology and Pathophysiology of Multiple Sclerosis; Richard Ransohoff and Don Joseph Mahad; 4. Epidemiology and Natural History of Multiple Sclerosis; Marcus Koch; 5. Multiple Sclerosis Genetics; Bruce Cree; 6. Symptoms and Signs of Multiple Sclerosis; Lael Stone; 7. Diagnosis of Multiple Sclerosis; Michael Hutchinson; 8. MRI in Multiple Sclerosis; Stephen Jones and Aliye Bricker; 9. Tools and Tests in Multiple Sclerosis; Robert Bermel; 10. Differential Diagnosis of Multiple Sclerosis; Megan Hyland and Jeffrey Cohen; 11. Overview of Present Treatment for Relapsing Forms of Multiple Sclerosis; Mary Alissa Willis and Richard Rudick; 12. Relapse Management in Multiple Sclerosis; Robert J. Fox; 13. Disease Modifying Therapies in Relapsing Multiple Sclerosis; Peter A. Calabresi and Jiwon Oh; 14. Primary Progressive Multiple Sclerosis; Kathleen Hawker; 15. Secondary Progressive Multiple Sclerosis; Alessandro Serra and Robert J. Fox; 16. Emerging Therapies for Multiple Sclerosis; Dan Ontaneda and Robert J. Fox; 17. Overview of Rehabilitation and Symptom Management in Multiple Sclerosis; Francois Bethoux; 18. Fatigue in Multiple Sclerosis; Susan Forwell; 19. Emotional Disorders in Multiple Sclerosis; Elias Khawam; 20. Cognitive Disorders in Multiple Sclerosis; Stephen Rao; 21. Epilepsy, Sleep Disorders, and Transient Neurological Events in Multiple Sclerosis; Alexander Rae-Grant; 22. Eye Symptoms, Signs, and Therapy in Multiple Sclerosis; Stephen Galetta; 23. Bulbar and Pseudo-Bulbar Dysfunction in Multiple Sclerosis; Devon S. Conway; 24. Pain/Dysesthesia Management in Multiple Sclerosis; John Foley, Kara Menning, and Cortnee Roman; 25. Bladder and Bowel Dysfunction in Multiple Sclerosis; Tina Sangeeta Mahajan and Bogdan Orasanu; 26. Sexual and Other Autonomic Dysfunction; Liz Crabtree-Hartman; 27. Spasticity Management in Multiple Sclerosis; Francois Bethoux and Mary Alissa Willis; 28. Multiple Sclerosis and Ambulation; Francois Bethoux and Keith McGee; 29. Health and Wellness in Multiple Sclerosis; Mary Rensel; 30. Complementary and Alternative Medicine in Multiple Sclerosis; Allen C. Bowling; 31. Pediatric Multiple Sclerosis; Amy Waldman and Lindsey Stull; 32. Womenís Issues; Bridgett Jeanne Billioux and Ellen Mowry; 33. Multiple Sclerosis in Older Age Groups; Bianca Weinstock-Guttman; 34. Societal Issues in Multiple Sclerosis; Deborah Miller; 35. Comprehensive Care in Multiple Sclerosis; Marge Henning; 36. Caregiving in Multiple Sclerosis; Amy Burleson Sullivan; 37. Neuromyelitis Optica; John R. Corboy and Matthew S. West; 38. Acute Disseminated Ecephalomyelitis; Timothy West; "

Editorial Review(s) 

"This concise, well-written book is surprisingly comprehensive for its size. It includes some unique features that make it easy to access what is in each chapter. It will be valuable as a reference, particularly for general neurologists, internists, family medicine physicians, and neurology residents and nurses who see and treat MS patients. "-Doody's Reviews