Head and Neck Cancers

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Head and Neck Cancers

SKU# 9780826137777

Evidence-Based Treatment


  • Athanassios Argiris MD, FACP
  • Robert L. Ferris MD, PhD, FACS
  • David I. Rosenthal MD, FACR, FASTRO


Head and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy.

Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes.

Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies.

Key Features:

  • Includes didactic clinical cases for each type of head and neck cancer
  • Numerous tables highlight FDA approved therapies and ongoing clinical trials
  • Provides evidence-based recommendations for treating head and neck cancers at each stage of the disease with conventional and novel treatment strategies
  • Covers strategies for managing acute and late complications to treatment
  • Includes access to the fully-searchable downloadable e-book

Product Details 

  • Publication Date June 28, 2018
  • Page Count 550
  • Product Form Hardback
  • ISBN 13 9780826137777

Table of Contents 


Epidemiology, Biology, Diagnosis and Staging

1. Epidemiology (Angela Mazul, Erich Sturgis, Andrew Olshan, Jose Zevallos)

2. Cytologic and histopathologic diagnosis of SCCHN (Adel K. El-Naggar, Michelle D. Williams)

3. Genomic landscape of SCCHN (Steffen Wagner, Jens Klussman, Ruud Brakenhoff)

4. HPV-related head and neck cancer biology (Farhoud Faraji, Carole Fakhry)

5. Imaging modalities for head and neck cancer (Rathan Subramaniam)


Established and emerging treatment modalities

6. Advances in radiation therapy techniques for SCCHN: Image-Guided RT Stereotactic, IMRT-VMAT, MRI-Linac and Simulation (Jussi Sillanpaa, C. Jillian Tsai, Nancy Y. Lee)

7. Proton therapy (Pierre Blanchard, G. Brandon Gunn, Steven J. Frank)

8. Transoral robotic surgery: advances and applications (Meghan T. Turner, F. Christopher Holsinger, Robert L. Ferris)

9. Induction chemotherapy: current and emerging role in SCCHN (Glenn J. Hanna, Robert I. Haddad)

10. Immunotherapy for head and neck cancer: rationale and clinical results (Jennifer Moy, Jennifer M. Johnson, Jessica Moskovitz, Robert L. Ferris, Athanassios Argiris)

11. EGFR-targeted therapy (Seront Emmanuel, Sandra Schmitz, Jean-Pascal Machiels)

12. Therapies targeting VEGF/angiogenesis and other novel targets and therapies in HNSCC (Sophie Stock-Martineau, Yanquin Dong, Denis Soulieres, Thomas Galloway)


Site-specific management

13. Oropharyngeal Cancer: HPV-Positive Disease (Christien A. Kluwe, Anthony J. Cmelak, Barbara A. Burtness)

Instructive case

14. Oropharyngeal cancer, HPV-not associated (Meghan T. Turner, F. Christopher Holsinger)

15. Oral Cavity - Surgical Approaches and Postoperative Treatment (Antoine Eskander, Jacques Bernier, Lisa Licitra, Paolo Bossi, Theodors N. Teknos)

16. Nasopharyngeal cancer (Wai Tong Ng, Oscar S.H. Chan, Henry C.K. Sze, Ka On Lam, Anne W.M. Lee)

17. Hypopharyngeal cancer (Moran Amit, Loren K. Mell, Cristina P. Rodriguez, Neil D. Gross)

18. Laryngeal cancer: organ preservation strategies (Arlene A. Forastiere, Jae Lee, Steven B. Chinn, Karim Boudadi, Avraham Eisbruch, Randal S. Weber)

19. Malignancies of the paranasal sinuses and skull base (Heather A. Osborn, Jong Chul Park, Nabil F. Saba, Pierre Blanchard, Derrick T. Lin)

20. Evaluation and treatment of metastatic lymphadenopathy from an unknown primary (Shirin Attarian, Richard Blake Ross, Shlomo A. Koyfman, Missak Haigentz, Jr.)

21. Salivary glands malignancies (Cristina P. Rodriguez, Jessica L. Geiger, Jon Mallen-St. Clair, Patrick K. Ha, Sue S. Yom, Adam S. Garden, David J. Adelstein)


Recurrent or metastatic disease

22. Locally recurrent SCCHN: salvage surgery, reirradiation (Antoine Eskander, Sharon A. Spencer, Corey J. Langer, Takashi Maruo, Ryuichi Hayashi, Sadamoto Zenda, James W. Rocco)

23. Recurrent or metastatic SCCHN: systemic therapy (Tomohiro Enokida, Susumu Okano, Makoto Tahara)


Supportive care and special patient groups

24. Supportive care and special patient groups (Rajesh V. Lalla, Douglas E. Peterson)

25. Dysphagia in Patients with Head and Neck Cancer (Katherine A. Hutcheson, Jan S. Lewin, Jolie Ringash, Mark Chambers)

26. Quality of Life Assessment and Patient Reported Outcomes in Head and Neck Cancer (Minh Tam Truong, Lisa Ann Kachnic)

27. Management of Head and Neck Cancers in the Elderly (Julie E. Bauman, Jessica L. Geiger)